Business managers view the implementation of management information system (MIS) as a tactic to combat competition by improving productivity, profitability and the level of information in respective of the forms of ownership, information enables the conceptualization and creation of new products and services by guiding decision makers in reaching a valid conclusion and making an informed decision regarding every area of their responsibilities. Using a structured questionnaire administered to fourty (40) selected staff of the WEMA BANK PLC, station road opposite post office Osogbo, Osun State, Nigeria and analyzing the obtained data with the descriptive method of statistical analysis, this study examines the role of management information system (MIS) on the service delivery in Nigeria Banking industry. The result obtained indicated that MIS is very important in an organization because no organization can survive, expand and attain meaningful development without information. Hence the importance of MIS cannot be over emphasized especially in the banking industry. Thus it is recommended that such information system needs to be strategically managed so as to bring about sound and profitable organization and thereby increase services delivery and organizational chance of surviving amidst daunting challenges.